Clinical Trials & Research Studies

Clinical research uses human volunteers to add to medical knowledge. Clinical research includes trials that test new treatments and therapies, genetic studies to explore ways in which a person’s genes may contribute to developing a disorder and epidemiological studies to understand the patterns, causes, and effects of health and disease.

The clinical trials information provided on this page is provided with support from Pfizer. 

Clinical Trials

Human clinical trials are a critical phase to bringing safe and effective treatments to market. Many tests are conducted before the clinical trial stage to determine whether potential treatments are appropriate for testing in people. It is through clinical trials that safe and effective drugs, therapies and potentially, a cure for alopecia areata will be discovered.

By participating in a clinical trial, you play an important role in the effort to develop effective treatments for alopecia areata. The decision to participate is very personal and should be made only after speaking with your health care provider and other individuals you trust. You can stop participation in a clinical trial at any time if new concerns arise or you lose confidence that its potential benefits outweigh its risks.

Clinical Trial Resources

ClinicalTrials.gov is a resource from the U.S. National Library of Medicine that offers up-to-date information for locating federally and privately supported clinical trials for a wide range of diseases and conditions. Visit ClinicalTrials.gov to review clinical trials that are recruiting particpants for studies on alopecia areata and other diseases.

Watch a webinar to learn more about clinical trials and how to search on ClinicalTrials.gov.

Download our guide to using ClinicalTrials.gov.

Download our worksheet, Clinical Trials and You, with questions to ask your doctor.

 

NAAF Postings for Clinical Trials and Research Studies

The National Alopecia Areata Foundation is committed to delivering accurate and reliable information to everyone affected by alopecia areata, and subsequently reviews many requests for postings about participation in research studies. The following is a current list of clinical trials and research studies working with NAAF  to recruit people with alopecia areata for particpation.

Disclaimer: NAAF provides research notices as an informational service to its community. NAAF is not conducting the study. This information does not represent a NAAF endorsement, but rather makes you aware that clinical studies are available for your participation if you choose. If you are presently under the care of a physician for alopecia areata, or other conditions, you should discuss clinical trial particpation  with your doctor before altering your treatment program. NAAF is not responsible for any adverse outcomes.

#Clinical Trials

A Phase 1b/2a Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of IMG-007 in Adult Alopecia Areata Participants with 50% or Greater Scalp Hair Loss

Learn More
Study type: Clinical Trials Posting date: 01/19/2024 Last updated: 01/19/2024 Status: Recruiting Phase: Phase 1b/2a Country: United States; Canada Eligibility:

18-65 years of age; diagnosed with alopecia areata with current episode of hair loss for at least 6 months but less than 8 years; have at least 50% scalp hair loss

Drug: IMG-007 Administration: Intravenous (IV) infusions Sponsor: Inmagene LLC Sponsor Link: Click here ClinicalTrials.gov: Click here
#Clinical Trials

Randomized, Double-Blind, Placebo-Controlled Phase 2a, Proof-of-Concept Trial of ADX-914 for the Treatment of Severe Alopecia Areata (SIGNAL-AA)

Learn More
Study type: Clinical Trials Posting date: 10/23/2023 Last updated: 10/23/2023 Status: Recruiting Phase: Phase 2a Country: United States Eligibility:

18 years to 75 years of age; diagnosed with alopecia areata

Drug: ADX-914 Administration: subcutaneous injection Sponsor: Q32 Bio Sponsor Link: Click here ClinicalTrials.gov: Click here
#Clinical Trials

A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata (BRAVE-AA-PEDS)

Learn More
Study type: Clinical Trials Posting date: 06/20/2023 Last updated: 06/20/2023 Status: Recruiting Phase: Phase 3 Country: United States Eligibility:

6 years to 17 years at the age of consent (enrollment will be fully sequential by age group, with adolescents (12 to less than 18 years old) enrolling before children (6 to less than 12 years old)

Drug: Baricitinib (LY3009104) or placebo Administration: Oral Sponsor: Eli Lilly Pharmaceuticals Sponsor Link: Click here ClinicalTrials.gov: Click here
#Clinical Trials

Phase 2a Study to Investigate Farudodstat in Adults with Alopecia Areata

Learn More
Study type: Clinical Trials Posting date: 05/22/2023 Last updated: 12/13/2023 Status: Recruiting Phase: Phase 2a Country: United States Eligibility:

18 years of age or older; diagnosed with alopecia areata; have at least 30% scalp hair loss

Drug: Farudodstat Administration: Oral Sponsor: ASLAN Pharmaceuticals Sponsor Link: Click here ClinicalTrials.gov: Click here
#Research Studies

Alopecia Areata and Vascular Health

Learn More
Study type: Research Studies Posting date: 10/31/2023 Last updated: 10/31/2023 Status: Recruiting Country: United States Eligibility:

18 years or older; diagnosed with alopecia areata; no history of heart attack or stroke

Drug: not applicable Administration: not applicable Sponsor: NYU Langone Health
#Clinical Trials

An Open-Label Subpopulation Study to Evaluate Efficacy and Safety of Baricitinib in Participants with Alopecia Areata that Self-Identify as Black or African American in Race

Learn More
Study type: Clinical Trials Posting date: 05/24/2023 Last updated: 01/29/2024 Status: Active/Fully Enrolled Phase: Phase 3 Country: United States Eligibility:

18yrs to ≤60 years for males (≤70 years of age for females); self-identify as either Black or African American in race; have severe or very severe alopecia areata

 

Drug: Baricitinib Administration: Oral Sponsor: Eli Lilly and Company ClinicalTrials.gov: Click here
#Clinical Trials

A Study to Evaluate the Safety of an Investigational Topical JAK Inhibitor Suspension in Adults with Alopecia Areata

Learn More
Study type: Clinical Trials Posting date: 05/22/2023 Last updated: 05/22/2023 Status: Recruiting Phase: Phase 1 Country: United States Eligibility:

18 to 70 years of age; have patchy alopecia areata

Drug: Investigational JAK Inhibitor Administration: Topical Sponsor: Arcutis Biotherapeutics Sponsor Link: Click here
#Clinical Trials

A Study in Children 6 years to 11 years of age with Severe Alopecia Areata (AA)

Learn More
Study type: Clinical Trials Posting date: 05/23/2023 Last updated: 07/27/2023 Status: Active/Fully Enrolled Phase: Phase 1 Country: United States Eligibility:

Note: Although this study is fully enrolled, additional pediatric studies are expected soon.

Drug: Ritlecitinib Administration: Oral Sponsor: Pfizer Sponsor Link: Click here ClinicalTrials.gov: Click here
#Clinical Trials

A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Alopecia Areata

Learn More
Study type: Clinical Trials Posting date: 02/21/2023 Last updated: 05/22/2023 Status: Active/Fully Enrolled Country: United States Eligibility:

18 Years to 65 Years of age; diagnosed with alopecia areata for at least 6 months; duration of current hair loss episode not exceeding 8 years

Drug: Deucravacitinib Administration: Oral Sponsor: Bristol Myers Squibb Sponsor Link: Click here ClinicalTrials.gov: Click here
#Clinical Trials

Study Evaluating Efficacy of Topical Squaric Acid Dibutyl Ester in Children and Adolescents with Alopecia Areata (SADBE-HD)

Learn More
Study type: Clinical Trials Posting date: 10/31/2022 Last updated: Status: Recruiting Country: United States Eligibility:

Ages 12-17; diagnosed with alopecia areata; at least 10% scalp hair loss

Drug: Squaric Acid Dibutyl Ester Administration: Topical Sponsor: Investigator-initiated ClinicalTrials.gov: Click here