Study to Investigate the Efficacy and Safety of an Investigational Medication in Children and Adolescents with Alopecia Areata

Study type: Clinical Trials Posting date: 06/26/2024 Last updated: 07/08/2024 Status: Recruiting Phase: Phase 2 Country: United States Eligibility:

Age 6-17; diagnosed with alopecia areata (30% or greater scalp hair loss)

Drug: Dupilumab Administration: Subcutaneous Injection Sponsor: National Institutes of Health (National Institute of Allergy and Infectious Diseases) ClinicalTrials.gov link: Click here Location: Multiple locations


Description:

A clinical research study is currently looking for children and adolescents (age 6-17) with alopecia areata who have lost 30% or more of the hair on their head to participate in a study of an investigational medication. 

During the course of this study, some people will receive the investigational medication and some will receive an inactive medication called a placebo. The study will explore whether the study drug is safe and can help AA patients regrow hair. 

Individuals may qualify to participate if they are: 

  • Are between 6 and 17 years of age 
  • have been diagnosed with alopecia areata 
  • have at least 30% scalp hair loss* 
  • Screening IgE ≥ 200 and/or have personal and/or familial history of atopy (including asthma, atopic dermatitis, allergic rhinitis, food allergy, or eosinophilic esophagitis) 

*Study doctor will assess your amount of hair loss. 

There are additional requirements as determined by a screening process. 

If you or someone you know is interested in joining this clinical trial, please visit this ClinicalTrials.Gov page for more information, or contact the study site closest to you: 

Icahn School of Medicine at Mount Sinai
New York, NY
Contact: Giselle Singer
Phone: 212-241-6033 or Email: giselle.singer@mssm.edu

University of California, Irvine
Irvine, CA
Contact: Marcos Hurtado
Phone: 949-824-7103 or Email: marcosh3@hs.uci.edu

Northwestern University
Chicago, IL
Contact: Ethan Yang
Phone: 312-503-5911 or Email: ethan.yang@northwestern.edu

Yale School of Medicine
New Haven, CT
Contact: Andrea DeClement
Phone: 203-785-5182 or Email: andrea.declement@yale.edu