A Study of 2 Doses of Ritlecitinib in People 12 Years of Age and Older With Alopecia Areata (ALLEGRO-100) - National Alopecia Areata Foundation | NAAF

A Study of 2 Doses of Ritlecitinib in People 12 Years of Age and Older With Alopecia Areata (ALLEGRO-100)

Study type: Clinical Trials Posting date: 07/28/2025 Last updated: 09/04/2025 Status: Recruiting Phase: Phase 3 Country: United States Eligibility:

This is a clinical trial for people who are at least 12 years old, have been diagnosed with alopecia areata and have lost at least 50% of the hair on their scalp.

Drug: LITFULO (ritlecitinib) Administration: pill taken by mouth Sponsor: Pfizer Sponsor Link: Click here ClinicalTrials.gov link: Click here Location: Multiple locations


Description:

The Allegro-100 clinical trial will determine if taking ritlecitinib at a dose of 100mg per day is safe, and if it can help more hair grow back. Ritlecitinib is currently FDA-approved at a dose of 50mg per day.

You may qualify to participate in this study if you:*
• Are at least 12 years old
• Have been diagnosed with alopecia areata and do not have hair loss caused by any other conditions
• Have lost at least 50% of the hair on your scalp
• Are in a current hair loss episode that has lasted 10 years or less

*There are additional requirements as determined by a screening process.

This study is taking place at locations throughout the United States.

More information on this trial is available at www.allegro100clinicaltrial.com.