Mechanistic Studies of Interleukin-7 Signaling Pathway in Alopecia Areata

Principal Investigator:
Zhenpeng Dai, PhD
Sponsoring Institution:
Columbia University
Principle Investigator


Mentored Young Investigator Grant Opportunities


If successful, this study will provide valuable information about the role of IL-7 in the onset of alopecia areata and therapeutic potential. Investment in a well-trained young investigator with a multidisciplinary background will likely lead to future alopecia areata research and NIH funding.


1) To understand the pathogenic role of IL-7 and its receptor blockade in alopecia areata using the C3H/HeJ mouse model; and 2) To assess IL-7 expression correlation in human alopecia areata skin or blood correlates with disease severity and parallels clinical status.