Mechanistic Studies of Interleukin-7 Signaling Pathway in Alopecia Areata

2016 to 2019
Zhenpeng Dai, PhD, Principal Investigator
Columbia University

Mentored Young Investigator Grant Opportunities


If successful, this study will provide valuable information about the role of IL-7 in the onset of alopecia areata and therapeutic potential. Investment in a well-trained young investigator with a multidisciplinary background will likely lead to future alopecia areata research and NIH funding.


1) To understand the pathogenic role of IL-7 and its receptor blockade in alopecia areata using the C3H/HeJ mouse model; and 2) To assess IL-7 expression correlation in human alopecia areata skin or blood correlates with disease severity and parallels clinical status.