Identifying pathogenic T cell receptor sequences in alopecia areata
Bridge Grant Opportunities
This study utilizes Next-Gen technology for DNA sequencing to learn about disease process and potentially establish a biomarker. If successful, findings could be applied to other autoimmune diseases. It is highly innovative and likely to lead to follow-on funding.
To determine the T cell receptors of hair follicle infiltrating T cells, and determine their frequency in affected skin, unaffected skin and if they are circulating in the blood.