Alopecia Areata Scalp Biopsy Biomarker Study

Year: 
2013
PI Name: 
Ali Jabbari, MD, PhD
Type:
Other
Status: 
Complete

Summary

The purpose of this project is to identify genetic biomarkers expressed in alopecia areata (AA) using skin and blood samples from the AA Registry & Biobank. This set of exploratory biomarkers will later be validated.

Impact

A biomarker is important to measure the progress of disease and/or the effects of treatment and will be crucial for monitoring improvements during clinical trials in alopecia areata and determining who may benefit from which treatment(s).

Publication

Jabbari A, Cerise JE, Chen JC, Mackay-Wiggan J, Duvic M, Price V, et al. Molecular signatures define alopecia areata subtypes and transcriptional biomarkers. EBioMedicine. 2016 May;7:240-7. doi: 10.1016/j.ebiom.2016.03.036