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Research

NAAF’s research program is committed to piecing together the puzzle presented by alopecia areata. Part of NAAF’s mission is to encourage research in alopecia areata, striving to find a cure or acceptable treatment. NAAF accomplishes the research mission by funding an acclaimed research grant program, and seeking out investigators worldwide in the areas of genetics, immunology and clinical research.

For 30 years, the National Alopecia Areata Foundation has represented the interests of patients and families affected by alopecia areata in all of its forms. We have done many things to develop the capabilities and influence of our organization while simultaneously providing needed information and support to our thousands of members. Since our inception, however, one goal has remained out of reach, until now: finding effective treatments that restore hair growth for people affected by alopecia areata.                              

Treatment Development Program

TDP logoWhile our capabilities and influence have grown stronger across the board, this past year produced an unprecedented advancement in our potential to find new and more effective treatments through our Treatment Development Program (TDP), a seven-year program that continues through 2016. With the recognition that treatments available or in development for other autoimmune diseases might also prove efficacious for alopecia areata, the Treatment Development Program takes a multipronged approach to developing safe and effective treatments. NAAF’s ability to move in this exciting direction is the result of our past commitment to sound and responsible research. Read more about the Treatment Development Program here>>>

NAAF has been at the forefront of many fruitful studies that yielded answers to some of the largest questions surrounding the autoimmune disease. We are committed to continuing this search until all of the questions about alopecia areata have been answered and the mechanisms of this disease are clearly understood. 

JID 2014 coverJID Publishes NAAF Research Summit Proceedings

The prestigious Journal of Investigative Dermatology (JID) has published the proceedings of NAAF’s 2012 Alopecia Areata Research Summit, From Basepairs to Bedside: Innovations in the Immunology & Clinical Science of Alopecia Areata, which analyzed progress that had been made in alopecia areata research over the previous two years and set the course for future research.  The supplement is being distributed to all subscribers of the Journal and researchers worldwide spreading the word and sparking new interest to further the progress of alopecia areata research.  To view article abstracts or order full texts, please go to http://www.nature.com/jidsp/index.html

Alopecia Areata Research Summit 2012 

From Basepairs to Bedside: Innovations in the Immunology & Clinical Science of Alopecia Areata

Everyone in attendance at the 2012 Alopecia Areata Research Summit, From Basepairs to Bedside: Innovations in the Immunology & Clinical Science of Alopecia Areata, discussed the progress that had been made in alopecia areata research after listening to scientific talks for two days. The summit was held in Bethesda, Maryland at the Hilton Garden Inn on Thursday, November 29 and Friday, November 30, 2012. The purpose of this summit was to discuss recent progress in understanding the pathogenesis of alopecia areata and chart the course for the future of translational research.

Wilma & AngelaAt the end of the Alopecia Areata Clinical Research Summit in October 2010 it was emphasized to our researchers from our guest scientists that we did not have a translational platform. Essential to that platform was  biomarker studies; new and established animal models; a uniform protocol;  incidence and prevalence studies; quality of life studies; burden of disease studies;  defined endpoints; defined hair measurement; more genetic and mechanistic studies;  genetic and immunological pathway studies; and collaboration with the FDA. Advances have been made in all these areas
Read full Summit Summary here>>


Drs Wilma Bergfeld and Angela Christiano, Co-Chairs of 2012 Research Summit .

 

Research Highlights

June 30, 2010:  Acclaimed Geneticist Finds Basis of Alopecia Areata

2010  -The Alopecia Areata Clinical/Translational Research Summit

2009 - Summary of Immunology Research Summit on Alopecia Areata 

2008 - Research Summit Determines Research Priorities

Research Journal Articles

New England Journal of Medicine, April 2012

Nature International Weekly Journal of Science, July 2010

Recorded Webinars 

November 29, 2010 - Webinar: What's All the Buzz About? with Dr. Angela Christiano

November 19, 2009  -Webinar: Alopecia Areata Immunology Research Summit Recap

Research Surveys

Relationship of Alopecia Areata to Lipid Lowering Agents

Treatments Survey

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